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Storing after your first use: You may keep "in-use" injection pens in the refrigerator or at room temperature

The mechanism involves central appetite suppression in the hypothalamus, but the gastric braking effect is real and unpleasant for many

19 Always consult with your health professional before stopping any medications or starting any new supplements

In some cases, that can support efficiency in indirect bonding and help reduce unnecessary bracket repositioning or wire adjustments

doi: 10.2337/dc06-2593 63

"Sip throughout the day to prevent constipation and help your gut cope with slower motility [how food moves through your gastrointestinal tract]," says Vocca